Craniofacial Characteristics of Thalassemia Major Patients

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Craniofacial Characteristics of Thalassemia Major Patients.

OBJECTIVE Thalassemias major are the most common autosomal recessive disorders; they are characterized by anomalies in the synthesis of the beta chains of hemoglobin and are often associated with varying degrees of craniofacial anomalies. The purpose of this study was to evaluate the craniofacial dimensions of β-thalassemia patients and to identify differences by comparing them to those of a co...

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Demographic and Laboratory Characteristics of β-Thalassemia Major Patients in Zahedan, Southeast of Iran

Abstract Background: Β-thalassemia is known as the most common inherited form of anemia worldwide and Iran. Considering high birth rate in the province, it seem necessary to study demographic factors and to assess common laboratory tests in order to find out whether  patients receive adequate care or not. Materials and Methods:  A cross–sectional descriptive analyti...

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Hypogonadism in thalassemia major patients

Despite recent advances in iron chelation therapy, excess iron deposition in pituitary gonadotropic cells remains one of the major problems in thalassemic patients. Hypogonadism, mostly hypogonadotropic hypogonadism, is usually detected during puberty. Early diagnosis and treatment are crucial for normal pubertal development and to reduce the complications of hypogonadism. The risks and benefit...

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Endocrine Disorders in Beta thalassemia Major Patients

Background Thalassemia is the most common hereditary disorder worldwide. The patient's’ survival is dependent on lifetime blood transfusion which leads to iron overload and its toxicity on various organs including endocrine glands. The study aimed to investigate endocrine disorders in patients with Beta-thalassemia major in the Southern Khorasan province, Iran. Materials and Methods In this des...

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Quality of life in patients with thalassemia major

Background With modern medical management, thalassemia major is now extending into adulthood and it is expected to have a negative impact on the quality of life (QOL) of the patients. The aim of this study was to evaluate quality of life in patients with thalassemia major. Materials and Methods This is an analytic case control study. Two hundred and fifty patients and 51 participants a...

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ژورنال

عنوان ژورنال: The Eurasian Journal of Medicine

سال: 2017

ISSN: 1308-8734,1308-8742

DOI: 10.5152/eurasianjmed.2016.150013