Contractile Strength during Variable Heart Duration Is Species and Preload Dependent

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Contractile Strength during Variable Heart Duration Is Species and Preload Dependent

We investigate the effect of beat-to-beat variability on cardiac contractility. Cardiac trabeculae were isolated from the right ventricle of rabbits and beagle dogs and stimulated to isometrically contract, alternating between fixed steady state versus variable interbeat intervals. Trabeculae were stimulated at physiologically relevant frequencies for each species (dog 1 and 4 Hz; rabbit 2 and ...

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ژورنال

عنوان ژورنال: Journal of Biomedicine and Biotechnology

سال: 2011

ISSN: 1110-7243,1110-7251

DOI: 10.1155/2011/294204