Clinical Significance of Clonal Hematopoiesis

Clonal hematopoiesis (CH) is associated with somatic mutations of the hematopoietic stem cells responsible for red blood cell formation. The incidence CH increases age and negative environmental factors. It particularly common in patients on chemotherapy, a greater than 10-fold increased risk hematological malignancy. also cardiovascular disease. Despite recent advances molecular genetic research, clinical translational aspects disease require more attention. However, as data accumulate, prevention onset progression will improve.