CHILD Syndrome: Effective Treatment of Ichthyosiform Naevus with Oral and Topical Ketoconazole

Bullous congenital ichthyosiform erythroderma: safe and effective topical treatment with calcipotriol ointment in a child.

Sir, Bullous congenital ichthyosiform erythroderma (BCIE), or epidermolytic hyperkeratosis (MIM# 113.800), is a rare disorder of keratinization associated with blistering in its early phase. It was first described by Jean-Louis Brocq in 1902 as érythrodermie congénitale ichthyosiforme avec hyperépidermotrophie. Although most cases are sporadic, familial cases show an autosomal dominant pattern ...

Congenital hemidysplasia with ichthyosiform naevus and limb defects (CHILD) syndrome without hemidysplasia

13% to 38%. Recently, we reported the effectiveness of rituximab, a monoclonal anti-CD20 antibody, as first-line therapy for pemphigus. Therefore, we have attempted to measure the utility of rituximab as first-line therapy for BP. From 2010 to 2012 we performed a retrospective case– control study in a referral centre in Taiwan, including patients with the generalized form of BP requiring system...

Comparison of topical and oral Ketoconazole in the treatment of intractable Seborrheic dermatitis

Background: Seborrheic dermatitis is one of the most common skin diseases. Objective: The purpose of this study was to compare the topical and oral ketoconazole in treatment of intractable cases of seborrheic dermatitis referring to Faghihi Hospital in Shiraz. Patients and Methods: This study was performed on 80 cases of intractable seborrheic dermatitis in 1376-1378. The patients were randomiz...

Comparison of a single oral dose of Fluconazole with Ketoconazole in the treatment of Tinea Versicolor

Background: Tinea versicolor is a superficial fungal infection caused by normal skin flora and treatable by topical and oral anti-fungal medications. Objective: To evaluate the clinical and paraclinical response and to compare possible side-effects of a single oral dose of fluconazole and ketoconazole in treatment of tinea versicolor. Patients and Methods: In this clinical trial, sixty-si...

Is Topical Clonazepam More Effective Than Oral Clonazepam in Treatment of Burning Mouth Syndrome (BMS)?