Cerebrospinal fluid absorption block at the vertex in chronic hydrocephalus: obstructed arachnoid granulations or elevated venous pressure?
نویسندگان
چکیده
منابع مشابه
In vitro model of cerebrospinal fluid outflow through human arachnoid granulations.
PURPOSE To describe and validate an in vitro model of the arachnoid granulation (AG) outflow pathway for cerebrospinal fluid (CSF), by using human AG cells grown on a filter membrane support and perfused in a modified Ussing chamber at pressures analogous to normal human intracranial pressures. METHODS Human AG cells were grown, characterized, seeded onto filter membranes, and perfused in the...
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Selective brain cooling is a system in a human that protects the brain from hyperthermia. Cool venous blood from head skin and upper respiratory tract drains into intracranial dural sinuses. In that region, cool blood in the dural sinuses decreases the temperature of the cerebrospinal fluid. Cerebrospinal fluid provides brain cooling. All cortical arteries to the brain pass the cerebrospinal fl...
متن کاملArachnoid Granulations and Arachnoid Villi in Mammals
There has been no general agreement regarding the presence of arachnoid granidations and arachnoid villi in mammals. This seems to have arisen from the fact that various workers have used different criteria in distinguishing between the two terms — 'granula tion' and 'villus'. Luschka (1852) was the first to. define the structure observed macroscopically as an 'arachnoid granulation', while fo...
متن کامل[Hypothesis of cerebrospinal fluid formation and absorption: from the clinical viewpoint of idiopathic normal pressure hydrocephalus].
The morphological features of disproportionately enlarged subarachnoid-space hydrocephalus (DESH), the core type of idiopathic normal pressure hydrocephalus, can not be explained by the classical theory of CSF absorption at the arachnoid villi and the hypothesis of CSF flow blocking at the convexity subarachnoid spaces. By using MRI Time-SLIP CSF flow imaging, we demonstrated that CSF freely mo...
متن کاملEx vivo model of cerebrospinal fluid outflow across human arachnoid granulations.
PURPOSE The brain's arachnoid membrane with granulations is an important biological barrier whose responsibilities include the transmission of cerebrospinal fluid (CSF) and the regulation of pressure. Membrane disturbance may cause changes that are difficult to replicate with animal models, suggesting the need for a model using human arachnoid membrane with granulations for the study of conditi...
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ژورنال
عنوان ژورنال: Fluids and Barriers of the CNS
سال: 2014
ISSN: 2045-8118
DOI: 10.1186/2045-8118-11-11