Cerebral Ischemia and Neuroprotection
نویسندگان
چکیده
منابع مشابه
P39: The Neuroprotection Effect of Erythropoietin in Cerebral Ischemia
Cerebral ischemia causes death of millions people all over the world, annually and also suffering more people from neurological deficits and neuromuscular disorders. In our country, 250 to 300 people experience mild to severe stroke, daily. In this study we reviewed 120 original paper selected from PubMED database. Our keywords were erythropoietin, anti-inflammatory, stroke, neuropathy and cere...
متن کاملProphylactic neuroprotection for cerebral ischemia.
BACKGROUND Treatments for acute ischemic stroke have evolved as knowledge about the pathophysiology of ischemic brain injury has advanced. Treatment strategies under development are aimed at offering neuroprotection acutely after focal cerebral ischemic injury, but delayed initiation of therapy may reduce efficacy. Pretreatment before ischemia begins could offer distinct advantages in patient g...
متن کاملNeuroprotection of G-CSF in cerebral ischemia.
In several experimental studies of cerebral ischemia, G-CSF exerts neuroprotective effects through different mechanisms, including mobilization of hematopoietic stem cells, anti-apoptosis, neuronal differentiation, angiogenesis and anti-inflammation. Hence, G-CSF not only inhibits neuron death, but also generates "new" neural tissue formation. A small pilot trial reports on the safety and feasi...
متن کاملOxytocin mediates social neuroprotection after cerebral ischemia.
BACKGROUND AND PURPOSE The reduced incidence, morbidity, and mortality of stroke among humans with strong social support have been well-documented; however, the mechanisms underlying these socially mediated phenomena remain unknown, but may involve oxytocin (OT), a hormone that modulates some aspects of social behavior in humans and other animals. METHODS In the present study, adult male mice...
متن کاملVEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia.
Vascular endothelial growth factor (VEGF) is an angiogenic protein with therapeutic potential in ischemic disorders, including stroke. VEGF confers neuroprotection and promotes neurogenesis and cerebral angiogenesis, but the manner in which these effects may interact in the ischemic brain is poorly understood. We produced focal cerebral ischemia by middle cerebral artery occlusion for 90 minute...
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ژورنال
عنوان ژورنال: Juntendo Medical Journal
سال: 1995
ISSN: 0022-6769,2188-2134
DOI: 10.14789/pjmj.41.207