منابع مشابه
Novel Vaccine Approaches
Shiver (Abstract S4) reviewed the strategy that he and his colleagues have developed for standardized assessment of T cells through development of short-term stimulation with peptide pools and ELISPOT assays that detect cytokine-secreting cells. Studies in HIV-infected individuals showed that ELISPOT assays can reproducibly and quantitatively measure cell-mediated responses to a variety of HIV ...
متن کاملComparing 3 Approaches for Making Vaccine Adoption Decisions in Thailand
Background The World Health Organization (WHO) has developed the Total System Effectiveness (TSE) framework to assist national policy-makers in prioritizing vaccines. The pilot was launched in Thailand to explore the potential use of TSE in a country with established governance structures and accountable decision-making processes fo...
متن کاملOld and new vaccine approaches.
The conventional, currently available vaccines, though quite successful, suffer from a few shortcomings which hamper future vaccine development. We present herewith some of the new approaches that are presently being pursued, including (1) the development of recombinant, or genetically engineered, vaccines which are based either on the expression of the relevant protective antigen and its formu...
متن کاملApproaches Applied to Vaccine Development
Vaccines represent one of the most cost-effective ways to prevent and treat diseases. The use of vaccines in the control of viral diseases represents an important milestone in the history of medicine. The genomic revolution brought us the possibility to scan genomes in the search of new and more effective vaccine candidates and the advancement of bioinformatics provided the framework for the ap...
متن کاملHepatitis C vaccine approaches phase II trial.
The fi rst prophylactic hepatitis C vaccine to reach human trials could enter phase II testing this year, a landmark for a fi eld that has faced many technical challenges since the virus was identifi ed in 1989. If this vaccine — or one of several other candidates — is successful, the public health impact could be substantial. Hepatitis C is a major cause of liver disease, including hepatocellu...
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ژورنال
عنوان ژورنال: The Cancer Journal
سال: 2010
ISSN: 1528-9117
DOI: 10.1097/ppo.0b013e3181eb33d7