Cell transformation by animal papillomaviruses
نویسندگان
چکیده
منابع مشابه
Animal Papillomaviruses
Systematic studies as well as anecdotal observations suggest that all mammals, some (or all) birds, and probably some other vertebrates and even nonvertebrates are infected by papillomaviruses (PVs). Historically, these observations were made by pathology examination, electron microscopy, or immunohistochemistry with polyclonal antibodies against the highly conserved L1 protein. In the last 15 ...
متن کاملThe immunology of animal papillomaviruses.
Papillomaviruses are species- and tissue-specific double-stranded DNA viruses. These viruses cause epithelial tumours in many animals, including man. Typically, the benign warts undergo spontaneous, immune-mediated regression, most likely effected by T-cells (especially CD4, but also CD8 subsets), whereas humoral immunity can prevent new infections. Some papillomavirus infections fail to regres...
متن کاملPapillomaviruses
Papillomaviruses (PVs) are a numerous family of small dsDNA viruses infecting virtually all mammals. PVs cause infections without triggering a strong immune response, and natural infection provides only limited protection against reinfection. Most PVs are part and parcel of the skin microbiota. In some cases, infections by certain PVs take diverse clinical presentations from highly productive s...
متن کاملWhy acute infections by human papillomaviruses matter
Most infections by human papillomaviruses (HPVs) are non-persistent. Yet, for HPVs, as 1 for many other oncoviruses, there is a striking gap between our detailed understanding of chronic 2 infections and our limited data on the early stages of infection. Here we argue that studying the 3 biology of acute infections by HPVs is necessary and timely. Disentangling early interactions will help 4 ex...
متن کاملHuman PaPillomaviruses
The HPV genome is divided into three regions: the long control region (LCR), which regulates viral gene expression and replication; the early (E) region, which encodes proteins required for viral gene expression, replication and survival; and the late (L) region, which encodes the viral structural proteins. The designations E and L refer to the phase in the viral life cycle when these proteins ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of General Virology
سال: 1992
ISSN: 0022-1317,1465-2099
DOI: 10.1099/0022-1317-73-2-217