Cell Salvage

Perioperative cell salvage

The National Blood Service for England collects, tests, processes, stores, and issues 2.1 million blood donations each year, and the optimal use of this scarce resource is of paramount importance. Allogeneic red blood cell (RBC) transfusion is associated with wellknown adverse effects. These include febrile, anaphylactic, and haemolytic transfusion reactions, transfusion-related acute lung inju...

Intraoperative cell salvage in revision hip surgery

Allogenic blood is a finite resource, with associated risks. Previous studies show intraoperative cell salvage (ICS) can reduce allogenic transfusion rates in orthopaedic surgery. However, there are concerns regarding efficacy and cost-effectiveness of ICS. This study was carried out to review ICS use in revision hip arthroplasty. All patients who underwent ICS and re-infusion between 2008 and ...

Salvage chemotherapy for refractory germ cell tumors.

At the University of Southern California (USC), it is our practice to begin by estimating the likelihood of a durable remission based on individual characteristics. Factors including pure seminoma, prior complete response (CR) to cisplatin therapy, low-volume metastases, and a testicular primary predict for cure with standard-dose salvage[1-4] and may help clinicians identify patients for whom ...

Indications and contraindications of cell salvage.

ultiple strategies can be applied to avoid allogeneic transfusion. The primary methods involve erythropoietin and iron supplementation, preoperative autologous donation, acute normovolemic hemodilution, and the application of cell salvage (CS) systems. Of these strategies, CS offers the greatest versatility in avoiding allogeneic red cell (RBC) transfusion. Many misconceptions and misinformatio...

Salvage therapy for diffuse large-cell lymphoma.