Calcification of glutaraldehyde-fixed porcine xenograft.
نویسندگان
چکیده
منابع مشابه
Calcification of glutaraldehyde-fixed porcine xenograft.
The clinical and light and electron microscopic findings are reported in a 14-year-old patient who died 12 months after mitral valve replacement with a Hancock prosthesis. Severe cusp calcification had led to immobilisation of the valve and stenosis. Calcification involved the substance of the valve cusps. The cause of the calcification in this patient is unknown.
متن کاملInfluence of blood contact on the calcification of glutaraldehyde-pretreated porcine aortic valves.
BACKGROUND The rat subcutaneous model reproduces clinically observed mineralization of bioprosthetic tissues. However, the effectiveness of antimineralization treatment can be overestimated in subcutaneous implants, since specimens using this model are not subjected to mechanical and dynamic stress or blood-surface contact. The purpose of this study was to evaluate the influence of blood contac...
متن کاملEffects of gamma irradiation on mechanical behavior and calcification of glutaraldehyde-fixed bovine pericardium.
OBJECTIVE To evaluate the effect of gamma irradiation on glutaraldehyde-fixed bovine pericardium. METHOD Glutaraldehyde-fixed bovine pericardium was exposed to gamma radiation (doses from 0 to 10000 Gy). Six samples from each of nine groups were evaluated by optic microscopy, and shrinking and mechanical tests and the denaturation temperature was determined. Additionally, they were subcutaneo...
متن کاملGlutaraldehyde-fixed bioprosthetic heart valve conduits calcify and fail from xenograft rejection.
BACKGROUND Glutaraldehyde fixation (G-F) decreases but likely does not eliminate the antigenicity of bioprosthetic heart valves. Rejection (with secondary dystrophic calcification) may be why G-F xenograft valves fail, especially in young patients, who are more immunocompetent than the elderly. Therefore, we sought to determine whether rejection of G-F xenograft occurs and to correlate this wit...
متن کاملPorcine Xenograft Valves
An analysis of 211 patients who had porcine xenograft valve replacements at Henry Ford Hospital between October 1971 and March 1974, was accomplished, with 100% follow-up. The follow-up period extended from 60-89 months after implantation. One hundred sixty-seven patients with 192 valves survived the perioperative period and were subjected to life table analysis. Hemodynamically significant por...
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ژورنال
عنوان ژورنال: Thorax
سال: 1978
ISSN: 0040-6376
DOI: 10.1136/thx.33.1.111