Beauvericin Inhibits Neuromuscular Transmission and Skeletal Muscle Contractility in Mouse Hemidiaphragm Preparation
نویسندگان
چکیده
منابع مشابه
The effects of pentoxifylline on skeletal muscle contractility and neuromuscular transmission during hypoxia
OBJECTIVES The objective of this study was to investigate the effects of pentoxifylline (PTX), a drug that is mainly used for indications related to tissue hypoxia, on hypoxia-induced inhibition of skeletal muscle contractility and neuromuscular transmission in mice. We hypothesized that chronic PTX treatment alters skeletal muscle contractility and hypoxia-induced dysfunction. MATERIALS AND ...
متن کاملField on the Contractility and in Neuromuscular Preparation Glycogen
The influence of static homogeneous magnetic fields, ranging from zero to le,OOO Oe, was measured on isolated frog neuromuscular preparation. On the fatigue curve, exposure of 10,OOO Oe caused the tension development to intensify gradually for the first 1-3 rnin and the time reached to a fatiguedmuscle, not responsiye to electrical stimulation, was reduced significantly <P < O,05) in comparison...
متن کاملEffects of Buthus eupeus Venom on Neuromuscular Transmission on Striated Muscle In Vitro
In this study, effects of Buthus eupeus venom on chick biventer cervices nerve-muscle preparation were investigated by twitch tension method. The venom, at 1.3 ?g/ml, increased contractile responses in indirect stimulations. These effects were milder in direct muscle stimulations. It also caused significant enhancement in postjunctional sensitivity as assessed by responses to exogenous acetylch...
متن کاملEffects of Buthus eupeus Venom on Neuromuscular Transmission on Striated Muscle In Vitro
In this study, effects of Buthus eupeus venom on chick biventer cervices nerve-muscle preparation were investigated by twitch tension method. The venom, at 1.3 ?g/ml, increased contractile responses in indirect stimulations. These effects were milder in direct muscle stimulations. It also caused significant enhancement in postjunctional sensitivity as assessed by responses to exogenous acetylch...
متن کاملImpaired neuromuscular transmission and skeletal muscle fiber necrosis in mice lacking Na/Ca exchanger 3.
We produced and analyzed mice deficient for Na/Ca exchanger 3 (NCX3), a protein that mediates cellular Ca(2+) efflux (forward mode) or Ca(2+) influx (reverse mode) and thus controls intracellular Ca(2+) concentration. NCX3-deficient mice (Ncx3(-/-)) present a skeletal muscle fiber necrosis and a defective neuromuscular transmission, reflecting the absence of NCX3 in the sarcolemma of the muscle...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Toxicological Sciences
سال: 2015
ISSN: 1096-6080,1096-0929
DOI: 10.1093/toxsci/kfv326