منابع مشابه
Update on clinical radiobiology
Radiation therapy is an important local cytotoxic modality for cancer treatment whose aim is to control the disease while minimising damage to normal tissue. The combination of different treatment modalities offers a more effective cure and reduction in normal tissue toxicity. However, the differences in genetic profiles can cause diverse treatment outcomes. Multidisciplinary research, where te...
متن کاملPhysical and Chemical Aspects of Basic Mechanisms in Radiobiology
This little book is the transcribed account of a Highland Park conference on this subject. It was attended by a representative group of persons interested in these basic mechanisms and the discussions were free and informative. The material has been quite well edited and yet has kept the tone of free discussion. This particular volume is somewhat physical and chemical in character and discusses...
متن کاملResults confounded by a disregard for basic dose-response radiobiology.
REPLY: We would like to thank Drs. Lam and Smits for their concerns and comments regarding the methodology in our study (1). The aim of our study was to answer the frequently occurring clinical question of whether a patient with low or no 99mTcmacroaggregated albumin (99mTc-MAA) uptake in metastatic lesions should undergo 90Y-radioembolization. The observation in our patient cohort with colorec...
متن کاملProton radiobiology and its clinical implications
Denser ionisation clustering and complex DNA damage in proton Bragg peaks far exceeds that seen with conventional X-rays. This results in more efficient cell sterilisation, quantified by the relative biological effectiveness (RBE). Currently, a 1.1 RBE is used to determine the clinical proton doses by dividing the usual X-rays dose by this amount. This number, derived from short-term experiment...
متن کاملProton Radiobiology
In addition to the physical advantages (Bragg peak), the use of charged particles in cancer therapy can be associated with distinct biological effects compared to X-rays. While heavy ions (densely ionizing radiation) are known to have an energy- and charge-dependent increased Relative Biological Effectiveness (RBE), protons should not be very different from sparsely ionizing photons. A slightly...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1994
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1994.352