منابع مشابه
Barrages of synaptic activity control the gain and sensitivity of cortical neurons.
Ongoing synaptic activity, ever present in cortical neurons, may vary widely in its amplitude and characteristics, potentially having a strong influence on neuronal processing. Intracellular recordings in layer 5 pyramidal cells in prefrontal and visual cortical slices maintained in vitro revealed spontaneous periods of synaptic bombardment. Testing the responsiveness of these cortical cells to...
متن کاملIntegration of Subthreshold and Suprathreshold Excitatory Barrages along the Somatodendritic Axis of Pyramidal Neurons
Neurons integrate inputs arriving in different cellular compartments to produce action potentials that are transmitted to other neurons. Because of the voltage- and time-dependent conductances in the dendrites and soma, summation of synaptic inputs is complex. To examine summation of membrane potentials and firing rates, we performed whole-cell recordings from layer 5 cortical pyramidal neurons...
متن کاملSpike-timing control by dendritic plateau potentials in the presence of synaptic barrages
Apical and tuft dendrites of pyramidal neurons support regenerative electrical potentials, giving rise to long-lasting (approximately hundreds of milliseconds) and strong (~50 mV from rest) depolarizations. Such plateau events rely on clustered glutamatergic input, can be mediated by calcium or by NMDA currents, and often generate somatic depolarizations that last for the time course of the den...
متن کاملSimilitude and scale effects of air entrainment in hydraulic jumps Similitude et effets d’échelle de l’entraînement d’air dans les ressauts hydrauliques
A hydraulic jump is characterized by some strong turbulence and air entrainment in the roller. New measurements were performed in two channels in which similar experiments with identical inflow Froude numbers and relative channel widths were conducted with a geometric scaling ratio of 2:1. Void fraction distributions showed the presence of an advection/diffusion shear layer in which the data fo...
متن کاملNeurobiology of Disease Modular Propagation of Epileptiform Activity: Evidence for an Inhibitory Veto in Neocortex
What regulates the spread of activity through cortical circuits? We present here data indicating a pivotal role for a vetoing inhibition restraining modules of pyramidal neurons. We combined fast calcium imaging of network activity with whole-cell recordings to examine epileptiform propagation in mouse neocortical slices. Epileptiform activity was induced by washing Mg 2 ions out of the slice. ...
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ژورنال
عنوان ژورنال: La Houille Blanche
سال: 1920
ISSN: 0018-6368,1958-5551
DOI: 10.1051/lhb/1920018