ARBOVIRUS HEMAGGLUTININ INHIBITORS IN NORMAL ANIMAL SERA

Antibody to Corynebacterium parvum in normal human and animal sera.

Using a microtiter bacterial agglutination test, we have estimated antibodies to Corynebacterium parvum in "normal" human and "normal" and immune animal sera. Widely differing levels of C. parvum antibodies were found in the normal human sera. The median titer for all 310 human sera was 1:128, whereas that for the 1- to 17-year and 18- to 50-year subgroups was 1:64 and 1:512, respectively. Anti...

Allantoic fluid as a source of arbovirus hemagglutinin.

Noninfectious hemagglutinins were prepared from the allantoic fluids of embryonated chicken eggs infected with Sindbis virus or with Murray Valley encephalitis virus.

Distinct glycoprotein inhibitors of influenza A virus in different animal sera.

Normal horse and guinea pig sera contain the glycoprotein inhibitor alpha 2-macroglobulin, which inhibits the infectivity and hemagglutinating activity of influenza A viruses of the H2 and H3 subtypes. In the current study, the presence of inhibitors of influenza A virus in pig and rabbit sera was investigated. Variants of influenza virus type A/Los Angeles/2/87(H3N2) that were resistant to hor...

Animal Sera for Transfusion Purposes

Zika Virus: A New Animal Model for an Arbovirus

In the latest issue of PLOS Neglected Tropical Diseases [1], Dowall and colleagues describe a novel small animal model for Zika virus infection. Along with two other reports in the recent weeks [2,3], this collection of papers marks an important turning point in Zika virus research and enables in vivo testing and evaluation of candidate vaccines and therapeutics. The authors show that type-1 in...