Antiviral activity of cystatin C against HIV

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Evaluation of cystatin C activities against HIV

BACKGROUND & OBJECTIVES Several host defense proteins known to possess antimicrobial activities are present on mucosal surfaces and are consequently found in body fluids of vertebrates. Naturally occurring protease inhibitors like cystatins, especially cystatin C (cys C), are abundantly present in human seminal plasma. Although its antiviral activity against herpes simplex virus (HSV) has been ...

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Introduction: The human immunodeficiency virus (HIV) is a threat to global health and the need for finding new methods of antivirus research, in particular against HIV has increased in recent years. In this study, we investigated the ability of the cold atmospheric pressure plasma jet (CAPPJ) using helium to inhibit the replication of HIV virions. Methods: Single cycle replicable HIV (SCR-HIV) ...

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ژورنال

عنوان ژورنال: Indian Journal of Medical Research

سال: 2015

ISSN: 0971-5916

DOI: 10.4103/0971-5916.159242