Antibacterial effect of bioactive glass incorporated in acrylic resins against Streptococcus Mutans and Lactobacillus Acidophilus activity in biofilm

Objective: The rough surfaces of removable appliances used in pediatric dentistry or orthodontics, may result inan environment for biofilm accumulation, yielding to enamel demineralization. This study aimed assess theeffects adding nanoparticles bioactive glass polymethylmethacrylate promote the antibacterial activityin acrylic resins. Material and Methods: Acrylic resin specimens (20x20x1mm3) were prepared by 2% or5% glass. control group without from mixtureof powder containing liquid monomer (n=10 per group). activity ofthe against Streptococcus mutans Lactobacillus acidophilus was investigatedthrough counting colony forming units (CFU). Data analyzed using a one-way analysis variance andTukey’s post hoc tests at significance level 0.05. Results: incorporation (p=0.001) 5%(p<0.001) reduced metabolic CFU L. acidophilus. For S.mutans,antimicrobial observed only with 5% concentration glass, this wasstatistically different (p<0.001). When exposed polymethyl methacrylatewith significant decrease compared (p<0.05). Conclusion:Adding into resins fabricating revealeda greater effect cariogenic bacteria tested. KEYWORDSAcrylic resins; Anti-bacterial agents; Bioactive glass; Dental materials; Pediatric dentistry.