Angiopoietin-2 blocking antibodies reduce early atherosclerotic plaque development in mice
نویسندگان
چکیده
منابع مشابه
Angiopoietin-2 blocking antibodies reduce early atherosclerotic plaque development in mice
OBJECTIVE Angiopoietin-2 (Ang-2) blocking agents are currently undergoing clinical trials for use in cancer treatment. Ang-2 has also been associated with rupture-prone atherosclerotic plaques in humans, suggesting a role for Ang-2 in plaque stability. Despite the availability of Ang-2 blocking agents, their clinical use is still lacking. Our aim was to establish if Ang-2 has a role in atheroma...
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ژورنال
عنوان ژورنال: Atherosclerosis
سال: 2015
ISSN: 0021-9150
DOI: 10.1016/j.atherosclerosis.2015.05.018