Alternative and Experimental Therapies of Mycobacterium abscessus Infections

Mycobacterium abscessus Complex Infections in Humans

Mycobacterium abscessus complex comprises a group of rapidly growing, multidrug-resistant, nontuberculous mycobacteria that are responsible for a wide spectrum of skin and soft tissue diseases, central nervous system infections, bacteremia, and ocular and other infections. M. abscessus complex is differentiated into 3 subspecies: M. abscessus subsp. abscessus, M. abscessus subsp. massiliense, a...

Inhaled therapies, azithromycin and Mycobacterium abscessus in cystic fibrosis patients.

Cystic fibrosis (CF) patients are at particularly high risk of developing lung disease caused by Mycobacterium abscessus complex (MABSC). Over the last 10 years, changes in CF treatment, with increasing use of inhaled therapies and low-dose azithromycin, have been accompanied by an increase in the prevalence of MABSC infections in CF patients. There is therefore some concern about the role of n...

1708Clinical Outcomes of Mycobacterium abscessus Infections in Miami, Florida

Florida Maroun Sfeir, MD; Marissa Tysiak, PharmD; Rossana Rosa, MD; Lo Kaming, MPH; Lilian Abbo, MD; Medicine, University of Miami Miller School of Medicine/ Jackson Memorial Hospital, Miami, FL; University of Miami Hospital, Miami, FL; Internal Medicine, Jackson Memorial Hospital/University of Miami Miller School of Medicine, Miami, FL; Divison of Biostatistics, Miami, FL; Medicine, Division o...

Clofazimine for Treatment of Mycobacterium abscessus Infections in Children

Mycobacterium abscessus Complex Infections: A Retrospective Cohort Study

Background Infections caused by Mycobacterium abscessus group strains are usually resistant to multiple antimicrobials and challenging to treat worldwide. We describe the risk factors, treatment, and clinical outcomes of patients in 2 large academic medical centers in the United States. Methods A retrospective cohort study of hospitalized adults with a positive culture for M. abscessus in Mia...