Allergic Reactions Captured by Voluntary Reporting

Nonimmediate allergic reactions induced by Mesna

Mesna (2-mercaptoethane sulfonate Na), a drug that alleviates cyclophosphamide (CYC)-induced hemorrhagic cystitis, is frequently used to treat cancer and collagen diseases. A 33-year-old woman presented with high fever during CYC-based induction therapy for systemic lupus erythematosus. Her final diagnosis was mesna-induced drug hypersensitivity. Although mesna is widely used, allergic reaction...

Reporting adverse drug reactions.

and are available from booksellers through the network of WHO sales agents. A list of these agents may be obtained by writing to the above address. (CIOMS) is a nongovernmental organization established jointly by the World Health Organization and UNESCO in 1949, with a mandate to collaborate with the United Nations and its specialized agencies. Its international membership, consisting of intern...

[Allergic drug reactions].

OBJECTIVE This review addresses the most recent published literature regarding drug allergy, in order to provide physicians with a background for a better understanding of this problem of great relevance for public health. SOURCES OF DATA The sources of data for obtaining the original and review articles published in the last 10 years were MEDLINE, Pubmed and Lilacs. The articles chosen for t...

Allergic reactions to drugs.

[Allergic reactions to food].

Food allergy is common disease that affects 11-26 million people in Europe. The incidence is estimated to be greater in children (5-8%) than the in adults (1-3%). Currently, the mechanisms of food allergy are not well characterized. There are a lot of open questions, for example: "Why do some individuals develop allergy to food? Why is some food more allergenic than other? Why do some children ...