Advances in Targeted Therapies for Pediatric Brain Tumors

Brain tumors: molecular biology and targeted therapies.

Brain tumors: molecular biology and targeted therapies M. E. Hegi, A. Murat, W. L. Lambiv & R. Stupp Laboratory of Tumor Biology and Genetics, Department of Neurosurgery, University Hospital Lausanne (CHUV), Lausanne; National Center of Competence in Research (NCCR) Molecular Oncology, Swiss Institute of Experimental Cancer Research (ISREC), Epalinges; Multidisciplinary Oncology Center, Univers...

Advances in Targeted Drug Delivery

Recent advances in the treatment of pediatric brain tumors.

Central nervous system (CNS) cancers are the second most frequent malignancy (and the most common solid tumor) in childhood. In recent years, significant advances in surgery, radiotherapy, and chemotherapy have improved survival in children with these tumors. However, a significant proportion of patients with CNS tumors suffer progressive disease despite such treatment. Advances in the understa...

Advances in the treatment of pediatric brain tumors.

Brain tumors are a heterogeneous group of neoplasms with different origins, pathobiologies, treatments and prognoses. The collective contributions from the fields of neuro-oncology, neurosurgery, radiation oncology, neurology, neuropathology, neuroradiology and molecular biology have all led to significant advances in the treatment of certain brain tumors. Ideas from these fields, under the coo...

Advances in Targeted Drug Delivery