Activating Architecture
نویسندگان
چکیده
منابع مشابه
Enzyme Architecture: Deconstruction of the Enzyme-Activating Phosphodianion Interactions of Orotidine 5′-Monophosphate Decarboxylase
The mechanism for activation of orotidine 5'-monophosphate decarboxylase (OMPDC) by interactions of side chains from Gln215 and Try217 at a gripper loop and R235, adjacent to this loop, with the phosphodianion of OMP was probed by determining the kinetic parameters k(cat) and K(m) for all combinations of single, double, and triple Q215A, Y217F, and R235A mutations. The 12 kcal/mol intrinsic bin...
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The first step of V(D)J recombination, specific cleavage at the recombination signal sequence (RSS), can be carried out by the recombination activating proteins RAG1 and RAG2. In vivo, the cleaved coding and signal ends must be rejoined to generate functional antigen receptors and maintain chromosomal integrity. We have investigated signal joint formation using deletion and inversion substrates...
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Human was created from both the natural and spiritual dimensions and has multimodal functions (e.g., cognitive, behavioral, affective, sensation, interpersonal relationship, and etc.). Having One-dimensional impression in life would provide anxiety predisposition for man, but then having an integrated and monotheistic view would result in an assimilated psychological discipline for him/her. The...
متن کاملStudy of prophenoloxidase activating system of freshwater crayfish (Pontastacus leptodactylus)
Phenoloxidase (Po) activity was measusred spectrophotometrically in serum, plasma and haemocytes (HLS) of the freshwater crayfish (Pontastacus leptodactylus). The highest activity was found in HLS suggesting that the haemocytes are the major source of the Po or its proform prophenoloxidase (proPO) in crayfish. Furthermore, the enzyme activity in serum samples was reduced after freezing the samp...
متن کاملStudy of prophenoloxidase activating system of freshwater crayfish (Pontastacus leptodactylus)
Phenoloxidase (Po) activity was measusred spectrophotometrically in serum, plasma and haemocytes (HLS) of the freshwater crayfish (Pontastacus leptodactylus). The highest activity was found in HLS suggesting that the haemocytes are the major source of the Po or its proform prophenoloxidase (proPO) in crayfish. Furthermore, the enzyme activity in serum samples was reduced after freezing the samp...
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ژورنال
عنوان ژورنال: Oz
سال: 2018
ISSN: 2378-5853
DOI: 10.4148/2378-5853.1577