Acanthamoeba castellanii trophozoites that survive multipurpose solutions are able to adhere to cosmetic contact lenses, increasing the risk of infection

Amoebae of the genus Acanthamoeba are etiological agents amoebic keratitis, for which up to now there is no treatment choice and one its main risk factors use contact lenses, including cosmetic lenses. Recently has been an increase in keratitis cases due Therefore, having a solution care lenses with efficient disinfectant effect that prevents adhesion trophozoites becomes essential. This study was carried out determine 8 multipurpose solutions on castellanii viability, efficiency two them prevent adherence (Acuvue 2, approved by US Food Drug Administration, Magic Eye CCL, not approved). After 3 h interaction, only AO Sept Plus, OPTI FREE Replenish, Renu Bio True Multiplus significantly reduced number viable respect control; at 6 12 Conta Soft Plus Multiplus, maintained inhibitory effect. Only Opti Free Pure Moist did reduce trophozoites. (selected their greater lesser antiamibic effect) trophozoite both lenses; however, more efficient, despite fact A. adhered similarly Our results show all evaluated, hundreds remain after several hours incubation. storage case MPS maintains potential in, wearers.