منابع مشابه
A screening test for assessing iron status.
Intervention strategies to combat iron deficiency anemia in developing countries may hasten the development of iron overload in patients with an inherited defect in hemoglobin synthesis. This risk could be diminished if there was a rapid and simple method available for detecting iron overload in population screening programs. We have developed such a method, which is in effect a semiquantitativ...
متن کاملScreening for hemochromatosis in a population with abnormal iron status.
Iron overload is frequently associated with hereditary or secondary alterations of iron metabolism.1,2 Hereditary hemochromatosis (HH), the most common genetic disease among northern European populations, is an autosomal recessive disorder characterized by an enhanced gastrointestinal absorption of iron that leads to progressive increase of iron stores and, eventually, to multiple organ dysfunc...
متن کاملUnsaturated iron-binding capacity: a screening test for C282Y hemochromatosis?
with “BD SST 1 double centrifugation” (P ,0.0001, paired t-test). Deming regression analysis yielded the following: slope 5 1.16 [95% confidence interval (95% CI), 1.03–1.29]; intercept 5 0.04 mg/L (95% CI, 0.02– 0.06 mg/L). Table 1 shows the assay values of the six apparently falsepositive results. These results prompted a second phase, during which the BD Thrombin sample was also centrifuged ...
متن کاملAssessing Iron Status in CKD Patients: New Laboratory Parameters
Anemia in patients with CKD is due to many factors. Erythropoiesis and iron homeostasis are impaired as a result of a complex chain of events, including the relative deficiency of erythropoietin, chronic inflammation, blood loss, decreased iron absorption and utilization, exogenous iron and erythropoietin acquisition via biologically unregulated mechanisms (blood transfusions and medicinal eryt...
متن کاملAssessing iron status: beyond serum ferritin and transferrin saturation.
The increasing prevalence of multiple comorbidities among anemic patients with chronic kidney disease has made the use of serum ferritin and transferrin saturation more challenging in diagnosing iron deficiency. Because serum ferritin is an acute-phase reactant and because the inflammatory state may inhibit the mobilization of iron from reticuloendothelial stores, the scenario of patients with ...
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ژورنال
عنوان ژورنال: Blood
سال: 1982
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v59.1.110.110