A rare primary thyroid mixed germ cell tumour: a case report

Germ cell tumours mostly occur in the gonads. Extragonadal site is rare and mainly located mediastinum, retroperitoneum pineal gland. tumour that occurs thyroid gland extremely rare. We present our first description of a patient with mixed germ primarily A 35 years old gentleman presented two months history swelling associated compressive symptoms. His neck ultrasound showed multinodular goiter suspicious nodule (TR4) FNAC revealed highly suggestive malignant lesion. Subsequently, mass progressively enlarged size causing acute upper airway obstruction made him collapsed at Emergency Department. Core biopsy TR4 lesion which could be or poorly differentiated carcinoma. Abnormal laboratory tests high concentration LDH, Alpha fetoprotein beta-HCG. He underwent emergency total thyroidectomy, debulking tracheostomy. Histopathology reported composed non-seminomatous area necrosis (30%), immature elements (80%), yolk sac (15%) embryonal carcinoma (5%). was scheduled for chemotherapy post operatively however he succumbed to illness due advanced sepsis.