A polymorphic minisatellite(pMS628) on chromosome 3 (D3S1084)
نویسندگان
چکیده
منابع مشابه
Polymorphic human somatostatin gene is located on chromosome 3.
Somatostatin is a 14-amino-acid neuropeptide and hormone that inhibits the secretion of several peptide hormones. The human gene for somatostatin SST has been cloned, and the sequence has been determined. This clone was used as a probe in chromosome mapping studies to detect the human somatostatin sequence in human-rodent hybrids. Southern blot analysis of 41 hybrids, including some containing ...
متن کاملIsolation and mapping of a polymorphic DNA sequence (cMCOD13) on chromosome 3 [D3S44].
SOURCE/DESCRIPTION; This cosmid HCOD13 has been isolated by an oligonucleotide (1) from a human genomic cosmid library. POLYMORPHISM: PvuII identifies >10 allelic VNTR polymorphisms with bands between 4.0 and 10.0 kb. TaqI, Rsal Mspl and Pstl identify the same VNTR polymorphism.
متن کاملIsolation and mapping of a polymorphic DNA sequence (pEFD134.7) on chromosome 3 [D3S45].
SOURCE/DESCRIPTION; A 4.3 lib Mspl fragment of cosmid EFD134 isolated by a HBV-3 oligonucleotide (1) was subcloned into AccI site of pUC18. POLYMORPHISM; Mspl identifies >10 allelic VNTR polymorphism with bands between 1.5 and 2.7 kb. Rsal and TaqI also identify the same VNTR polymorphism. FREQUENCY: With Mspl, 80 % heterozygosity were observed in 85 unrelated Caucasians. NOT POLYMORPHIC FOR: n...
متن کاملIsolation and mapping of a polymorphic DNA sequence pYNZ86.1 on chromosome 3 (D3S30).
SOURCE/DESCRIPTION: A 3.3 kb Hindi 11 fragment from cosmid YNZ86 was subcloned into the Hindlll site of pUClB. POLYMORPHISM: Mspl identifies a two allele polymorphism (Ml : 2.0 kb, M2 : 1.9 kb) with constant bands at 2.6 and 1.7 kb. PvuII also identifies a two allele polymorphism (PI : 1.1 kb, P2 : 0.8 kb) with a constant band at 1.5 kb, but this observation has not been verified by pedigree st...
متن کاملIsolation and mapping of a polymorphic DNA sequence (pEFD145) on chromosome 3 [D3S32].
SOURCE/DESCRIPTION: A 4.1 kl) TaqI fragment from cosmid EFD145 was subcloned into the AccI site of pUC18. POLYMORPHISM: Rsal identifies a two allele polymorphism (Rl : 2.4 kb, M2 : 1.4 and 1.0 kb) with a constant band at 0.9 kb. TaqI also identifies a two allele polymorphism (Tl : 5.0 kb, T2 : 4.1 kb) without a constant band, but this observation has not been verified by pedigree studies. FREQU...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1991
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/19.19.5447-a