A Genomic Island Defines Subspecies-Specific Virulence Features of the Host-Adapted Pathogen Campylobacter fetus subsp. venerealis

A genomic island defines subspecies-specific virulence features of the host-adapted pathogen Campylobacter fetus subsp. venerealis.

The pathogen Campylobacter fetus comprises two subspecies, C. fetus subsp. fetus and C. fetus subsp. venerealis. Although these taxa are highly related on the genome level, they are adapted to distinct hosts and tissues. C. fetus subsp. fetus infects a diversity of hosts, including humans, and colonizes the gastrointestinal tract. In contrast, C. fetus subsp. venerealis is largely restricted to...

A genomic island defines subspecies - specific virulence features of the host adapted 1 pathogen

A genomic island defines subspecies-specific virulence features of the host adapted 1 pathogen Campylobacter fetus subsp. venerealis. 2 3 Gregor Gorkiewicz, 1, 2* Sabine Kienesberger, 1, 2 Caroline Schober, 1 Sylvia R. Scheicher, 1 4 Christian Gülly, 3 Rudolf Zechner, 1 and Ellen L. Zechner 1 5 6 Institute for Molecular Biosciences, Karl-Franzens-University of Graz, Humboldtstrasse 50/I, 7 8010...

Campylobacter fetus subsp. venerealis adhesion to MDBK cells.

Is Campylobacter fetus subspecies venerealis infection a cause of reproductive failure in dairy cows in Iran?

Bovine genital campylobacteriosis is one of the most economically important diseases of dairy cattleresulting in lowered fertility, embryo mortality and abortion, repeated returns to service, reduced pregnancyrates and extended calving intervals. While the occurrence of repeat breeding syndrome and abortions arereported from many Iranian dairy cattle farms, little information is available regar...

Comparative Genome Analysis of Campylobacter fetus Subspecies Revealed Horizontally Acquired Genetic Elements Important for Virulence and Niche Specificity

Campylobacter fetus are important animal and human pathogens and the two major subspecies differ strikingly in pathogenicity. C. fetus subsp. venerealis is highly niche-adapted, mainly infecting the genital tract of cattle. C. fetus subsp. fetus has a wider host-range, colonizing the genital- and intestinal-tract of animals and humans. We report the complete genomic sequence of C. fetus subsp. ...