631 A Comparison of the Microbiology Profile for Two-Stage Revision Surgery in Periprosthetic Joint Infection (PJI) of Primary Knee Arthroplasty and Lower Limb Endoprostheses for Tumour Surgery

Abstract Aim To compare the microbiology organisms responsible for PJI in patients who underwent two-stage revision of infected primary knee replacement with oncological endoprostheses lower limb a single institution. Method 118 were treated 2-stage surgery arthroplasty and between 1999 2019. 74 had 44 to eradicate infection tumour resection. All microbiological data from first stage sampling was collected analysed retrospectively. Patient host extremity criteria categorised according MSIS Host Extremity Staging System. Results According System, grade cohort significantly better than PJI(p<0.05). The incidence multi-drug resistance (MDR) higher, 36% endoprosthetic group compared 17% (p=0.001). MDR most common coagulase-negative staphylococcus. Gram-positive isolated more 80% cultures both cohorts. Coagulase-negative staphylococcus (CoNs) commonest gram-positive organism E Coli Gram-negative groups. Conclusion Patients presenting after have higher an cohort. Pre-operative meticulous methods intra-operatively are extremely important these patients.