118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects

Author ' s response to reviews Title : 118 SNPs of Folate - Related Genes and Risks of Selected Congenital

the evaluation of language related engagment and task related engagment with the purpose of investigating the effect of metatalk and task typology

abstract while task-based instruction is considered as the most effective way to learn a language in the related literature, it is oversimplified on various grounds. different variables may affect how students are engaged with not only the language but also with the task itself. the present study was conducted to investigate language and task related engagement on the basis of the task typolog...

Spina bifida and its associated skull defects.

Some degree of interest has recently been aroused in the question of the occurrence and incidence of spina bifida. Despite the efforts made by many theorists in the past, its mode of production still remains obscure; it is known' that fundamentally there is a defective formation of the mesodermal tissues surrounding the primitive neural plate, and that the process of chondrification and subsequ...

Spina bifida and other neural tube defects.

NTDs, resulting from failure of the neural tube to close during the fourth week of embryogenesis, are the most common severely disabling birth defects in the United States, with a frequency of approximately 1 of every 2000 births. Neural tube malformations involving the spinal cord and vertebral arches are referred to as spina bifida, with severe types of spina bifida involving protrusion of th...

Genetic variation of infant reduced folate carrier (A80G) and risk of orofacial and conotruncal heart defects.

How folate reduces the risks of congenital anomalies is unknown. The authors focused on a gene involved in folate transport-reduced folate carrier-1 gene (RFC1). Using data from a California case-control study (1987-1989 births), the authors investigated whether the risks of orofacial clefts or conotruncal heart defects were influenced by a polymorphism of infant RFC1 or by an interaction betwe...